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It’s all in your head: Scientist now believes his pioneering work on gluten allergy was wrong

By Scott Kaufman
Sunday, May 25, 2014 10:24 EDT
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Fat Man In Front Of A Plate Of Spaghetti on shutterstock
 
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The researcher whose work led scientific credence to claims that those without celiac disease — which causes an immune response in the small intestines in the presence of gluten — still benefit from a gluten-free diet has performed another, more rigorous study that leads him to believe that there is no such thing as non-celiac gluten sensitivity (NCGS).

In 2011, Peter Gibson, a professor of gastroenterology at Monash University in Australia, published a study that found that gluten proteins cause gastrointestinal distress even in people who don’t suffer from celiac disease. This study helped provided scientific backing to the “gluten-free” diet fad, but Gibson believed that the evidence on which the fad was based wasn’t thorough enough, so in 2013 he performed another study.

In the 2013 study, he provided his subjects with three diets: two “treatment” diets, one of which was low-gluten, one of which was high-gluten; and a baseline diet. He found that subjects reported similarly increased gastrointestinal distress on both the low- and high-gluten “treatment” diets compared to the baseline.

Gibson then performed a second experiment to ensure the suitability of the whey protein in the baseline diet, and discovered that when he repeated the experiment with the baseline diet labeled as “treatment,” his subjects reported increased gastrointestinal distress on it as well.

The subjects were responding to what the medical community calls “the nocebo effect,” in which a harmless substance causes negative reactions because the subjects in an experiment expect it to.

Gibson was forced to draw a conclusion that directly contradicted the one he drew in 2011: “In contrast to our first study,” he wrote, “we could find absolutely no specific response to gluten.”

["Fat Man In Front Of A Plate Of Spaghetti" on Shutterstock]

Scott Kaufman
Scott Kaufman
Scott Eric Kaufman is the proprietor of the AV Club's Internet Film School and, in addition to Raw Story, also writes for Lawyers, Guns & Money. He earned a Ph.D. in English Literature from the University of California, Irvine in 2008.
 
 
 
 
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