Police have charged Prime Minister David Cameron's ex-media chief Andy Coulson with phone hacking as a long-running press scandal lapped at the door of Downing Street.

Former tabloid editor Rebekah Brooks will also be charged at a later date, police confirmed.

The Crown Prosecution Service (CPS) said eight current or former employees of Rupert Murdoch's now defunct News of the World would answer hacking charges, which carry a maximum sentence of two years in prison.

In total, police issued 19 separate charges of conspiring to illegally intercept the voicemails of some 600 people, including Hollywood stars Brad Pitt, Angelina Jolie and Jude Law as well as politicians and crime victims.

Prosecutors said the other people targeted included Wayne Rooney and Paul McCartney.

"I have concluded that a prosecution is required in the public interest in relation to each of these eight suspects," senior prosecutor Alison Levitt said in a live televised announcement.

The others charged include Stuart Kuttner, the News of the World's former managing editor, former news editor Greg Miskiw, former head of news Ian Edmondson, former chief reporter Neville Thurlbeck, and reporter James Weatherup.

The last person is private investigator Glenn Mulcaire, who was jailed for phone hacking for six months in 2007.

All eight will appear in court in London on August 16, according to the CPS.

Australian-born media tycoon Murdoch, 81, was forced to close the weekly News of the World a year ago amid a storm of revelations that its staff hacked into the voicemail messages of a murdered schoolgirl and a slew of public figures.

Coulson, 44, edited the News of the World from 2003 to 2007 and went on to become Cameron's spokesman, but resigned from that post in January 2011 after he was questioned over the scandal. He was arrested last year.

"I will fight these allegations when they eventually get to court," Coulson told reporters outside his house.

Brooks, also 44, was editor of the tabloid from 2000 to 2003 and went on to edit The Sun before going on to become chief executive of News International, Murdoch's British newspaper group.

"I am not guilty of these charges," she said in a statement released by her lawyers. "I did not authorise, nor was I aware of, phone hacking under my editorship."

Brooks was charged in May with conspiracy to pervert the course of justice by allegedly trying to cover up evidence relating to phone hacking during the frantic last days of the News of the World.

She became close to the prime minister after she married racehorse trainer Charlie Brooks, who attended Eton with Cameron, and their friendship has proved an embarrassment to the Conservative leader.

Thurlbeck also protested his innocence, saying he had "always operated under the strict guidance and advice of News International's lawyers and... the newspaper's editors".

The announcement came the same day the Leveson inquiry into press ethics, which was set up in the wake of the News of the World scandal, held its last scheduled hearing.

Senior judge Brian Leveson said he would produce his report -- which could cause a seismic shift in the way the press is regulated -- "as soon as I can".

In total the inquiry has heard eight months of evidence from around 470 witnesses, ranging from celebrities and members of the public targeted by hacking, to media barons, police chiefs and politicians.

The Guardian, which exposed much of the scandal, said Tuesday's developments highlighted the need for Leveson to ensure plurality in the media.

"Murdoch's size, influence, aggression and dominance were directly related to the scandal that led to Leveson," Wednesday's editorial claimed.

"There would have been no Leveson without the scrutiny of a newspaper -- this newspaper -- which asked questions the police, parliament, regulator and many other journalists wouldn't ask. In the end, plurality trumps all."

Police launched an investigation into hacking in January 2011 and have so far arrested 24 people under Operation Weeting and 41 under Operation Elveden, a related probe into corrupt payments to public officials.

A further seven have been arrested under Operation Tuleta, which is investigating alleged computer hacking and privacy infringement.