WASHINGTON (Reuters) - The Democratic-led Senate will vote at 4 p.m. EDT on Thursday on its landmark immigration bill, Senate Democratic Leader Harry Reid announced.

The White House-backed measure is expected to win strong bipartisan approval, and then go to the Republican-led House, which plans to draft its own bill, one without the Senate's proposed pathway to citizenship for millions of undocumented immigrants.

Reid set the vote after the Senate cut off debate on the bipartisan measure with a vote of 68-32. Fourteen Republicans joined all 54 members of the Senate Democratic caucus in ending three weeks of debate on the measure by invoking cloture.

In addition to providing a 13-year pathway to citizenship for illegal immigrants, the bipartisan bill would double to 40,000 the number of federal agents on the U.S.-Mexican border and help provide American businesses with needed low- and high-skilled workers.

(Reporting By Thomas Ferraro; Editing by Sandra Maler)