To fight opioid crisis, researchers take new shot at developing vaccine against addictive drugs
Marco Pravetoni, seen Wednesday, Dec. 1, 2021, will lead University of Washington's new center devoted to developing vaccines and medications against substance use disorders. - Alan Berner/The Seattle Times/TNS

SEATTLE — It's been nearly 50 years since a group of researchers in Chicago reported an extraordinary finding: They'd created a vaccine against drug addiction and an early test showed it might work. The scientists provided a rhesus monkey with drugs like heroin and cocaine; it became addicted. But when they injected the monkey with a compound they'd developed — one designed to coax the immune system into fighting addictive drugs as if they were pathogenic invaders — the animal stopped seeking drugs. Their finding, published in the top scientific journal Nature in 1974, heralded a new frontier ...