WATCH: Comedian George Lopez leads Phoenix audience in rousing 'F*ck Donald Trump' chant

Appearing at the Phoenix Celebrity Theater Saturday night, popular late night comedian George Lopez went off on a rant about GOP presidential frontrunner Donald Trump's comments calling Mexicans "rapists." He then led the crowd in a profane chant using a colorful Spanish expletive.

Saying, "This country is better with Latinos in it, "to the cheers of the audience, the Hispanic comedian paced the circular stage, shouting out "Donald Trump," with the audience responding back, "F*ck that puto."

The pejorative "puto" is often used as a disparaging name for a homosexual or male prostitute.

This is not the first time Lopez has used the expression for a politician. Lopez previously used the chant in 2008 to describe then-President George W. Bush.

Watch the video below, uploaded to YouTube by Bridget Figueroa: