WATCH LIVE: Explosion at Ariana Grande concert results in 'confirmed fatalities' at Manchester Arena

Police in Manchester, England are responding to a serious incident at a venue where Ariana Grande was performing, Reuters reports.

"Emergency services responding to serious incident at Manchester Arena," Greater Manchester Police said. "Avoid the area."

NBC Nightly News reports “confirmed fatalities” at the venue. Witnesses say they heard loud explosions, prompting panic in the arena.

BREAKING on @NBCNightlyNews:

Police: Deaths and injuries after reports of explosion at Manchester Arena in England. https://t.co/eF09lzCKeh

— NBC Nightly News (@NBCNightlyNews) May 22, 2017

Watch a live feed of the response below, via Sky News: