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Comedian Chelsea Handler responded to Republican vice presidential nominee J.D. Vance over the weekend after he insulted women by claiming the country was being run by "childless cat ladies."

In a viral video shared on X, Handler noted that Vance's remarks were "ruffling a few feathers."

During an appearance on MSNBC on Sunday, Transportation Secretary Pete Buttigieg, acting as a private citizen, joined the pile-on afflicting Sen. J. D. Vance that has been unrelenting since the Ohio Republican was selected by Donald Trump chose him to be his 2024 presidential running mate.

Speaking with host Jen Psaki, the former Democratic mayor of South Bend, Indiana subtly leaned into the narrative that Americans find Vance "weird" based on a history of comments over the years that have the Trump campaign reeling.

As the man known as "Mayor Pete" explained to the host, "Where do you start? You know, they selected somebody who really reminded many Americans of why they are put off by the turn that the Republican party has taken in the last two years."

RELATED: 'Control yourself, man': Fox News goes off the rails as pundit melts down over Harris

A Fox News segment went off the rails on Sunday after conservative pundit Ben Domenech shouted down left-leaning contributor Laura Fink.

During a Fox News Media Buzz program segment, host Howard Kurtz pointed out that the network's latest poll suggested Vice President Kamala Harris and former President Donald Trump were essentially tied in swing states.

During an appearance on CBS' "Face The Nation," Sen. Lindsey Graham (R-SC) faced off with host Robert Costa when confronted with Sen. J.D. Vance's criticism of "childless women" with cats having no stake in the future of America.

The Ohio Republican, who was chosen by Donald Trump to be his vice presidential running mate in the 2024 election, has been swamped by criticism since Vice President Kamala Harris became the Democratic nominee to the point that GOP insiders fear Vance has done irreparable damage to the ticket.

On Sunday, Costa asked the unmarried South Carolina Republican, "Senator, I understand your focus on Vice President Harris, the presumptive Democratic nominee, but there are also many Americans who do not have children. You're also not just a senator, you're a political strategist , you work informally with former president Trump and so many Republicans. You have a political mind, is it a mistake for Senator Vance to keep talking about Americans who don't have children when it comes to a national campaign?"

"Right, yeah. I don't have children," Graham parried before adding, "But I'm going to vote for J.D. and Trump because I think we'll be safer and more prosperous and more secure. I want to end the Biden-Harris debacle."

RELATED: 'Disgusting': J.D. Vance hits back at Jennifer Aniston for criticizing 'cat ladies' remark

"You know you should never say anything to hurt anybody's feelings, but when you look at all these interviews by J.D., but he was talking about how the Democratic party has abandoned the traditional family."

He later added, "So this idea of trying to marginalize J.D. and make him some kind of bad person is not going to work. He's not a bad person, he's a good person. He has served his country honorably and is going to help president Trump win."

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Fox News host Maria Bartiromo admitted that Vice President Kamala Harris had experienced a "meteoric rise" but blamed it on former President Barack Obama.

"Obama reportedly pulling all the strings from four years of the Biden-Harris administration to the meteoric rise of Kamala," Bartiromo said during an interview with conservative Peter Schweizer, president of the Government Accountability Institute (GAI).

On Sunday morning, CNN host Jake Tapper faced an avalanche of criticism after inviting Sen. Tom Cotton (R-AR) on to talk about the changing presidential race now that Vice President Kamala Harris appears to be the 2024 Democratic presidential candidate.

What ended up happening was Tapper sitting back and letting Cotton ramble with no fact-checking as Arkansas Republican went on extensive rants about Harris — all of them current MAGA talking points about the vice president who Republicans are trying to paint as more liberal than Sen. Bernie Sanders (I-VT).

ABC host Martha Raddatz called out a surrogate for Donald Trump after the former president told a group of Christians that they would never have to vote again if he was elected in 2024.

"You won't have to do it anymore," Trump told the group recently. "You won't have to vote anymore. My beautiful Christians, I love you, Christians."

Transportation Secretary Pete Buttigieg rebuffed Fox News host Shannon Bream on Sunday after she suggested that Vice President Kamala Harris was unqualified to lead the country.

During an interview on Fox News Sunday, Bream noted that one conservative New York Times columnist had called Harris's candidacy "anti-democratic."

An MSNBC panel of pundits couldn't help but laugh on Sunday after former President Donald Trump promised "so much electricity" that Americans would be saying, "Please, President, we don't want any more electricity."

During a Sunday panel discussion on MSNBC, host Alicia Menendez read a quote from a recent Trump rally.