Joe Manchin to vote against Neera Tanden — likely sinking her OMB nomination

Sen. Joe Manchin (D-WV) says that he will oppose Neera Tanden's nomination to lead the Office of Management and Budget, CNN reports.

"I believe her overtly partisan statements will have a toxic and detrimental impact on the important working relationship between members of Congress and the next director of the Office of Management and Budget," he said in a statement.

The Senate is split 50-50, with Democrats having control due to the ability of Vice President Kamala Harris to cast tie-breaking votes. But Democrats' one-vote margin means any defection by a member of their caucus could give a united Republican caucus the ability to block the nomination.

Read his full statement below: