Comedian Stephen Colbert said Monday he had no qualms about mocking his sister Elizabeth Colbert-Busch, though he plans to support her candidacy for a U.S. House seat in South Carolina.

"I'm willing to break the jewel of my creation to try to do something for her," he told CNN's Jake Tapper. "I'm not worried what it would do to me or my show to try to help her as myself, not as my character, and you know if people think that is not the right thing for me to do, I don't care. She is my sister and I am willing to help her."

Elizabeth is running as a Democrat for the House seat vacated by Republican Tim Scott after he was appointed to the U.S. Senate. She is expected to win Tuesday’s special congressional primary and could potentially face disgraced former South Carolina Gov. Mark Sanford in May. Though Colbert plans to help his sister's political campaign while he is out-of-character, she is fair game while he is in-character.

"I said, if you do something funny, I'm making jokes about you," he said.

"But she won't," Tapper responded.

"Yeah, sure she will," Colbert replied. "She's now a politician. Of course she will. She's perfectly human."

Colbert has already campaigned on behalf of his sister, saying he supported her mostly because "she’s sane."

Watch video, uploaded to YouTube by CNN, below: