A single vaccine shot, rather than the recommended triple dose, may be enough to protect women against cervical cancer, a study said on Wednesday.
If further work validates the findings, there could be major gains for campaigns to vaccinate young women in poor countries, the authors said.
The research looked at Cervarix, which with another vaccine, Gardasil, is being rolled out to shield young girls from the human papillomavirus (HPV) which causes cervical cancer.
Cervarix is a so-called bivalent vaccine, targeting two types of virus — HPV 16 and 18 — that together are to blame for about 70 percent of cases.
The vaccine was initially approved to be given in three doses over six months, although some countries have cautiously switched to a two-dose schedule.
The new research, published in the journal The Lancet Oncology, suggests that this easier regimen could be taken even further.
The authors reported on an aspect of two big trials to test Cervarix among 7,500 women in Costa Rica aged 18-25 and more than 18,500 women aged 15-25 in the Asia-Pacific, Europe and the Americas.
Women in these trials were randomly assigned to receiving either Cervarix in three doses, or a hepatitis A vaccine.
However, 543 of the women in the Cervarix group only received one dose, mainly because their vaccination was discontinued due to pregnancy.
Four years after the trial took place, the researchers checked the health of the volunteers.
They found there was no difference in cancer rates among those who had received Cervarix, regardless of the number of doses they had received.
The authors, led by Cosette Wheeler of the University of New Mexico in Albuquerque, call for a new randomised study to see if these findings hold true on a larger scale and beyond just four years.
If the good news is confirmed, the big beneficiaries would be poor countries.
Cervical cancer is notoriously called a “silent killer” of women. It is the fourth commonest cause of cancer among women, and tragically is often diagnosed too late.
“If one dose is sufficient, it could reduce vaccination and administration costs as well as improve uptake,” said co-author Aimee Kreimer of the US National Cancer Institute.
“This is especially important in less developed regions of the world, where more than 80 percent of cervical cancer cases occur.”
HPV is easily spread by sexual intercourse.
In addition to cervical cancer, it can also cause genital warts and cancer of the anus and penis. For that reason, doctors in the United States and other countries recommend pre-teens of both sexes be vaccinated.
Trump: ‘Any Jewish people’ who vote for Democrats have ‘a total lack of knowledge or great disloyalty’
President Donald Trump on Tuesday accused the majority of Jewish American voters of having "a total lack of knowledge or great disloyalty" because they support Democrats.
While discussing Reps. Ilhan Omar (D-MN) and Rashida Tlaib (D-MI) during a talk with reporters, the president said he couldn't imagine any Jewish American voting for the Democrats due to the congresswomen's comments about Israel.
"I think any Jewish people that vote for a Democrat, I think it shows either a total lack of knowledge or great disloyalty," Trump said.
Conservative columnist blasts GOP as ‘partisan hacks for whom hypocrisy is second-nature’
On Tuesday, President Donald Trump once again ripped into The Squad, this time to undercut an emotional press conference in which Rep. Rashida Tlaib (D-MN) described the conditions her Palestinian relatives live under.
“Sorry, I don’t buy Rep. Tlaib’s tears. I have watched her violence, craziness and, most importantly, WORDS, for far too long,” the president tweeted. “Now tears? She hates Israel and all Jewish people. She is an anti-Semite. She and her 3 friends are the new face of the Democrat Party. Live with it!”
Sorry, I don’t buy Rep. Tlaib’s tears. I have watched her violence, craziness and, most importantly, WORDS, for far too long. Now tears? She hates Israel and all Jewish people. She is an anti-Semite. She and her 3 friends are the new face of the Democrat Party. Live with it!
‘They’re with me all the way’: Trump uses Log Cabin Endorsement as shield when asked about destroying LGBT rights
President Donald Trump has not publicly acknowledged the early endorsement he received late last week from the gay Republican group Log Cabin Republicans, but he was quick to mention it when asked about his record of destroying the civil rights of LGBTQ people.
Trump bragged, “they’re with me all the way, and I just got a big endorsement from the Log Cabin group,” during a Tuesday afternoon press gaggle, according to pool reports.