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The real ‘Jaws’: Great white shark’s genetic secrets revealed

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The great white shark, one of the most fearsome predators in the world’s oceans in both fact and fiction, is a formidable creature — right down to its genes.

Scientists on Monday said they have decoded the genome of Earth’s largest predatory fish, detecting numerous genetic traits that help explain its remarkable evolutionary success, including molecular adaptations to enhance wound healing as well as genomic stability such as DNA repair and DNA damage tolerance.

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The great white shark, whose scientific name is Carcharodon carcharias, boasts a very large genome, 1-1/2 times bigger than the human genome.

In theory, large genomes with a lot of repeated DNA, like this shark possesses, and its large body size should promote a high incidence of genome instability, with much more DNA and many more cells seemingly vulnerable as targets for damage through an accumulation of routine mutations.

Just the opposite seems to be the case for this shark, thanks to adaptations in genes involved in preserving genome integrity.

“This knowledge, in addition to providing understanding into how sharks work at their most fundamental level — their genes — may also be useful in downstream applications to human medicine to combat cancers and age-related diseases that result from genome instability,” said Mahmood Shivji, director of the Save Our Seas Foundation Shark Research Center and Guy Harvey Research Institute at Nova Southeastern University in Florida.

This species, star of the 1975 Hollywood blockbuster “Jaws” and its multiple sequels, roams the world’s oceans, primarily in cool coastal waters.

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Gray with a white underbelly and torpedo-shaped body, it can reach 20 feet (6 meters) long, weigh 7,000 pounds (3.18 tonnes) and dive to nearly 4,000 feet (1,200 meters) deep. It uses its mouthful of large, serrated teeth to rip into prey including fish, seals and dolphins, swallowing mouth-sized chunks of flesh whole.

Sharks are an evolutionary success story, thriving for more than 400 million years. Our species appeared roughly 300,000 years ago.

The great white shark also displayed genetic adaptations in several genes that play fundamental roles in wound healing. For example, a key gene involved in producing a major component of blood clots was found to have undergone adaptations.

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“These adaptations and enrichments of essential wound-healing genes may underlie the ability of sharks to heal from wounds so efficiently,” said Cornell University’s Michael Stanhope, co-leader of the research published in the Proceedings of the National Academy of Sciences.

Reporting by Will Dunham; Editing by Sandra Maler

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‘Brutal and unacceptable’: Calls for arrest of NYPD cop who put woman in the ER during protests

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The Speaker of the New York City Council is demanding accountability for a NYPD officer caught on tape violently striking a woman during protests of police violence.

Video of the incident appeared on social media on Friday. The video appears to show the cop running up a shoving the woman, launching her off her feet.

She is reportedly now in the ER after suffering a serious seizure.

"This officer needs to be charged with assault," Speaker Cory Johnson posted on Twitter. "Hard to watch. Brutal and unacceptable."

This officer needs to be charged with assault.

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‘I’m getting shot’: Shocking video shows police in Louisville hitting journalists with pepper bullets

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Police fired pepper bullets at a camera crew doing a live broadcast of the police violence protests in Louisville on Friday evening.

"WAVE 3 News reporter Kaitlin Rust appeared to have been hit by rubber bullets reportedly fired by an LMPD officer during a protest in downtown Louisville," the station reported.

Rust was wearing a fluorescent safety vest at the time of the incident.

"I'm getting shot," she shouted.

The news anchor asked, "who are they aiming that at?"

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Law enforcement files discredit Brian Kemp’s accusation that Democrats tried to hack the Georgia election

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It was a stunning accusation: Two days before the 2018 election for Georgia governor, Republican Brian Kemp used his power as secretary of state to open an investigation into what he called a “failed hacking attempt” of voter registration systems involving the Democratic Party.

But newly released case files from the Georgia Bureau of Investigation reveal that there was no such hacking attempt.

The evidence from the closed investigation indicates that Kemp’s office mistook planned security tests and a warning about potential election security holes for malicious hacking.

Kemp then wrongly accused his political opponents just before Election Day — a high-profile salvo that drew national media attention in one of the most closely watched races of 2018.

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