Quantcast
Connect with us

Scientists find earliest clues of Parkinson’s in brain

Published

on

Scientists said Thursday they had found the earliest signs of Parkinson’s disease in the brain years before patients show any symptoms, a discovery that could eventually lead to better screening for at-risk people.

Parkinson’s, a neurodegenerative disorder that causes patients movement and cognitive problems, is estimated to effect up to 10 million people worldwide.

ADVERTISEMENT

It is diagnosed by a build-up in the brain of a specific protein, a-synuclein, the cause of which is unclear.

However some people are born with a genetic mutation that makes them almost certain to develop the disease at some stage in their life.

Researchers from King’s College London compared data from 14 individuals carrying the mutation with that of 65 non-genetic Parkinson’s patients and 25 healthy volunteers.

They found that changes in the serotonin system in the brains of Parkinson’s sufferers started to malfunction well before other symptoms occurred.

ADVERTISEMENT

“We found that serotonin function was an excellent marker for how advanced Parkinson’s disease has become,” said Heather Wilson, from the university’s Institute of Psychiatry, Psychology and Neuroscience.

“Therefore, brain imaging of the serotonin system could become a valuable tool to detect individuals at risk of Parkinson’s diseases, monitor their progression and help with the development of new treatments.”

Suspected causes of the disease before the study included levels of the neurotransmitter dopamine, and there is growing evidence of a possible link between Parkinson’s and gut function, though this is poorly understood.

ADVERTISEMENT

“Picking up on the condition earlier and being able to monitor its progression would aid the discovery of new and better treatments that could slow the loss of brain cells in Parkinson’s,” said Beckie Port, research manager at Parkinson’s UK, who was not involved in the study.

“Further research is needed to fully understand the importance of this discovery, but if it is able to unlock a tool to measure and monitor how Parkinson’s develops, it could change countless lives.”

The research was published in The Lancet Neurology.

ADVERTISEMENT


Report typos and corrections to: [email protected].
READ COMMENTS - JOIN THE DISCUSSION
Continue Reading

Breaking Banner

‘This is INSANE’: National security experts shocked by Pompeo’s saber-rattling towards Turkey

Published

on

National security experts are floored seeing the warmongering coming from Secretary of State Mike Pompeo, who said Monday that he was prepared to go to war with Turkey.

“We prefer peace to war,” Pompeo told CNBC. “But in the event that kinetic action or military action is needed, you should know that President Trump is fully prepared to undertake that action.”

He didn't want to give specifics, however, saying he wanted to let the president announce things himself.

Continue Reading

Breaking Banner

The tangled web of Rudy Giuliani’s associations with questionable characters in the Ukraine scandal

Published

on

Washington Post political analyst Philip Bump has created a link analysis of the tangled web President Donald Trump's attorney Rudy Giuliani finds himself caught in.

According to the report, Giuliani isn't only linked to Lev Parnas and Igor Fruman, the two associates indicted and arrested after lunch with them a few weeks ago. Giuliani is linked to a chorus of people now outed for being involved in the Ukraine scandal.

Continue Reading
 

CNN

WATCH: CNN displays the Constitution’s Emoluments Clause as Trump rambles about it being ‘phony’

Published

on

Two days after intense pressure forced President Donald Trump to back down from his plan to host the 2020 G7 summit at his resort in Doral, Florida, the president dismissed the Constitution's anti-corruption clause—which his plan would have violated—as "phony."

"You people, with this phony Emoluments Clause," Trump told reporters at a White House press conference on Monday, responding to allegations that hosting the meeting of foreign leaders at his own property would be a conflict of interest.

Continue Reading
 
 
Help Raw Story Uncover Injustice. Join Raw Story Investigates for $1 and go ad-free.
close-image