Supporters of Julian Assange on Friday vowed to fight his extradition to the United States after Britain approved a US request for the WikiLeaks founder to face trial over the publication of secret military files.
"We're not at the end of the road here. We're going to fight this. We're going to use every appeal avenue," Stella Assange, who married the Australian publisher earlier this year, told reporters.
His lawyer, Jen Robinson, urged US President Joe Biden to drop the charges and called on the Australian government to press for her client's release.
"We will appeal this all the way through the British courts and if necessary to the European Court of Human Rights," she added.
The Assange case has become a cause celebre for media freedom and his supporters accuse Washington of trying to muzzle reporting of legitimate security concerns.
He is wanted to face trial for violating the US Espionage Act by publishing military and diplomatic files in 2010 and could face up to 175 years in jail if found guilty, although the exact sentence is difficult to estimate.
The UK interior ministry earlier announced that Home Secretary Priti Patel had approved the extradition order but that he had 14 days to appeal.
That sets up yet another court hearing in the long-running legal saga, which began in 2010 after WikiLeaks published more than 500,000 classified US documents about the wars in Iraq and Afghanistan.
His supporters have held frequent rallies to protest the planned deportation, accusing Washington of a politically motivated campaign as Assange, 50, had exposed US war crimes and a cover-up.
WikiLeaks said the decision was a "dark day for press freedom and for British democracy" and alleged that Assange had been on a CIA hit-list.
"Julian did nothing wrong. He has committed no crime and is not a criminal. He is a journalist and a publisher, and he is being punished for doing his job," the group said in a statement.
Extradition was a work of "revenge" and an attempt to "try to disappear him into the darkest recesses of their prison system for the rest of his life to deter others from holding governments to account".
Amnesty International said the government's approval of the extradition "sends a chilling message" to journalists and exposed Assange to torture and ill-treatment if he were kept in solitary confinement.
The human rights monitor's secretary-general Agnes Callamard said diplomatic assurances that he would be well treated were not to be trusted, she added.
The Home Office, however, said there were no grounds for Patel to block the extradition order, which was made on April 20.
"In this case, the UK courts have not found that it would be oppressive, unjust or an abuse of process to extradite Mr Assange," a spokesperson said.
"Nor have they found that extradition would be incompatible with his human rights, including his right to a fair trial and to freedom of expression, and that whilst in the US he will be treated appropriately, including in relation to his health."
Legal experts said Assange's decision to appeal sets up potentially months of legal hearings.
He would first need permission to appeal from the High Court. If that was granted, the hearing might not be until early next year.
"He could also make an application to the European Court of Human Rights," said Kate Goold, an extradition lawyer at London firm Bindmans.
"Once you get to the European Court of Human Rights, it's a very, very slow process," added another specialist Rebecca Niblock, from lawyers Kingsley Napley.
"Extradition is a very lengthy process and it is very unlikely that this will be the end of it."
Assange has been held on remand at a top-security jail in southeast London since 2019 for jumping bail in a previous case accusing him of sexual assault in Sweden.
That case was dropped but he was not released from prison after serving time for breaching bail on the grounds he was a flight risk in the US extradition case.
His supporters have tried to secure his release and block his extradition on the grounds that he was a suicide risk if held in punishing isolation in US custody.
Assange, who got married behind bars in March, spent seven years at Ecuador's embassy in London to avoid being removed to Sweden.
He was arrested when the government changed in Quito and his diplomatic protection was removed.