A drug-resistant infection contributed to Hugh Hefner’s death
Playboy's Hugh Hefner with Holly Madison and Bridget Marquardt (Luke Ford/Wikimedia Commons)

Playboy mogul Hugh Hefner died of cardiac arrest and respiratory failure after contracting septicemia, an infection caused by e. coli that is resistant to drugs, according to The Blast. Hefner died on Sept. 27 in his home surrounded by his wife, Crystal Harris, and his four children. He was 91 years old. RELATED: Ellen DeGeneres offers…