WATCH: Chuck Todd flips out after Democratic strategist calls Trump a 'psychopath'
Meet the Press host Chuck Todd, strategist David Plouffe -- (NBC screen grab)

In a rare example of pushback on NBC's Meet the Press, host Chuck Todd grew visibly agitated and interrupted a Democratic analyst after he described GOP presidential nominee Donald Trump as a "psychopath."

Following two weeks of Trump and his surrogates playing TV doctor and claiming former Secretary of State Hillary Clinton suffers from - among other maladies -- "dysphasia," political operative David Plouffe's offhand comment about Trump mental wellness caused Todd to blast him.

Stating Trump has been trying to turn his campaign around by appealing to "the middle of the electorate," the former campaign manager for Barack Obama said it wouldn't work.

"I mean, basically you have a psychopath running for president, " Plouffe said. "He's the clinical definition, by the way."

"Wait a minute," Todd interrupted. "Let me ask you, wait a minute.  Do you really think -- diagnosing people on air, and I assume you don't have a degree in psychology. Is that fair? I mean we're jumping to conclusions here and I think this is what has voters a little frustrated."

Plouffe replied with an adequate layman's description of observable Trump traits.

"Well, listen. Grandiose notion of self worth, pathological lying, lack of empathy and remorse," Plouffe recited. "I think he does, although I don't have a degree."

Plouffe went on to say that electoral map shows Trump has no chance of being elected.

Watch the video below via YouTube: