The host of "Real Time" on HBO had a live studio audience on Friday evening.
During his opening monologue, Maher noted that cases of coronavirus are dropping in America.
"They're down because we're over the spike from the holiday season when Americans just, of course, didn't follow the rules and f*cked up and met with each other, so that's why it's down, but now we're coming up on Valentine's Day -- for once being a loser with no love life is a good thing," he explained.
Maher went on to discuss Trump's second impeachment, which he described as a yearly event that is "like Groundhog's Day, but with a weasel."
He went on to cover the battle within the GOP and fights over Rep. Liz Cheney (R-WY) and Rep. Marjorie Taylor Greene (R-GA).
"A five hour meeting they had on this where they defended themselves, Liz Cheney laid out her strong anti-terrorist credentials and then Marjorie Taylor Greene laid out her strong pro-terrorist credentials," he said.