Famed comedian rips RFK Jr in scathing take down at Hollywood Bowl charity event
Secretary of Health and Human Services Robert F. Kennedy Jr. delivers remarks while President Donald Trump listens during a press conference to announce a link between autism and childhood vaccines and the use of popular pain medication Tylenol for pregnant women and children, claims which are not backed by decades of science, at the White House in Washington, D.C., on September 22, 2025. REUTERS/Kevin Lamarque

Comedian John Mulaney had a fierce smackdown for Robert F. Kennedy Jr. in front of a large audience at the Hollywood Bowl this weekend.

Mulaney was performing at the "Night Of Too Many Stars," a benefit for autism programs featuring top comics at the Los Angeles venue, when he dug into Kennedy's role and reputation in the Trump administration, TMZ reported. He started the monologue off by describing his own past experience with Kennedy.

"This is the best benefit I've done since Robert F. Kennedy Jr.'s Riverkeeper's benefit 10 years ago," Mulaney said, impersonating Kennedy's voice.

"If you don't know Bobby, and I know him as Bobby, that's how much he shouldn't be in the government, I know him," Mulaney joked. "He's comedy adjacent, you know? He's married to that woman from 'Curb Your Enthusiasm' and cheats on her like a dog but he likes to be around comedy people. Sorry for the pearl clutch here, Westside people who know exactly what I'm talking about. Sorry to drop that public domain information on the Hollywood Bowl."

Mulaney mocked Kennedy's work for the organization, which has aimed to keep the Hudson River in New York clean.

"That's how good he is at jobs. His old job was keeping the Hudson River, whose native fish is tied-off used condom, clean," Mulaney quipped, mocking Kennedy again in his voice, "'And now I'm in charge of your bones and your tummy.' Stupid f---. Your thing can't be the measles."

He also made fun of Kennedy's skeptical approach to vaccines and the measles outbreak, saying in Kennedy's voice: "Can I be in charge of your body?"